Clinical study demonstrates sleep and mood improvements after low-frequency rTMS in insomnia disorder, indicating EEG functional connectivity can serve as a predictive biomarker.
Low frequency rTMS could improve sleep quality and depressive moods in patients with insomnia disorder. Moreover, electroencephalographic functional connectivity would potentially be a robust biomarker for predicting the therapeutic effects.
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Shi et al. (2021) studied this question.
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