Preliminary findings suggest a potential physiological link between gut microbial fermentation and peripheral chemoreflex sensitivity in heart failure, warranting further investigation.
Our preliminary results, derived from a small, uncontrolled physiological experiment conducted in 12 H F patients, imply a link between the upper gut microbial fermentation capacity and the baseline peripheral chemoreflex sensitivity in this population. Given the exploratory and non-randomized design, these findings should be interpreted with caution, and larger controlled studies are needed to confirm the nature and clinical relevance of this association.
Mikołajczak et al. (Thu,) studied this question.