Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response

Ben Sidders; Pei Zhang; Kelly Goodwin; Greg O’Connor; Deanna L. Russell; Alexandra Borodovsky; Joshua Armenia; Robert McEwen; Bolan Linghu; Johanna C. Bendell; Todd M. Bauer; Manish R. Patel; Gerald S. Falchook; Melinda S. Merchant; Gayle P. Pouliot; J. Carl Barrett; Jonathan R. Dry; Rich Woessner; Kris F. Sachsenmeier

doi:10.1158/1078-0432.ccr-19-2183

Ask about this paper

Answers are grounded in this paper and cite their sources.

Abstract

These data support the adenosine pathway as a mediator of a successful antitumor immune response, demonstrate the prognostic potential of the signature for immunotherapy, and inform patient selection strategies for adenosine pathway modulators currently in development.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Sidders et al. (2020) studied this question.

synapsesocial.com/papers/69d957a45e5bcb4e3b835aa6 https://doi.org/10.1158/1078-0432.ccr-19-2183

View at Publisher

Ask AI

Bookmark

Share

Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response

Ask about this paper

Abstract

Discussion

Cite This Study

Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response

Ask about this paper

Abstract

Discussion

Cite This Study

Keep reading

Keep reading