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March 19, 2022BMC Infectious DiseasesOpen Access

High prevalence of pre-treatment HIV drug resistance in Papua New Guinea: findings from the first nationally representative pre-treatment HIV drug resistance study

Janet Gare Ben Toto Percy Pokeya Linh‐Vi Le Nick Dala Namarola Lote Bangan John Abel Yamba Kevin Webby SOLI Joshua DeVos Heather Paulin Nick Wagar Du-Ping Zheng Takeshi Nishijima Peniel Boas Angela Kelly‐Hanku Anup Gurung

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Abstract

PNG has a high PDR prevalence rate, especially to NNRTI-based first-line therapies. Our findings suggest that removing NNRTIs as part of first-line treatment is warranted and will lead to improving viral suppression rates in PNG.

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Gare et al. (2022) studied this question.

synapsesocial.com/papers/69d95c878988aeabbe684f7b https://doi.org/10.1186/s12879-022-07264-y

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysisMeta-Analysis · 2017 · 414 citations
2Risk Factors and Mortality Associated With Resistance to First-Line Antiretroviral TherapyCross-Sectional Study · 2015 · 30 citations
3Factors associated with HIV and syphilis infection among female sex workers in three cities in Papua New Guinea: findings from Kauntim mi tu, a biobehavioral surveyOriginal Research · 2020 · 18 citations
4Presence of HIV drug resistance in antiretroviral therapy-naive and -experienced patients from Papua New GuineaOriginal Research · 2014 · 11 citations
5High Levels of Transmitted HIV Drug Resistance in a Study in Papua New GuineaOriginal Research · 2017 · 10 citations

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