Why the study?
Does chronic inflammation mediate the association between lifecourse socioeconomic disadvantage and type 2 diabetes risk?
Does chronic inflammation mediate the association between lifecourse socioeconomic disadvantage and type 2 diabetes risk?
Chronic inflammation mediates a substantial portion of the increased risk of type 2 diabetes associated with lifecourse socioeconomic disadvantage.
Supports inflammation as mediator of socioeconomic diabetes disparities; hypothesis-generating for targeted interventions pending trials.
In the present study, chronic inflammation explained a substantial part of the association between lifecourse socioeconomic disadvantage and type 2 diabetes. Further studies should be performed to confirm these findings in population-based samples, as the Whitehall II cohort is not representative of the general population, and to examine the extent to which social inequalities attributable to chronic inflammation are reversible.
No takes yet. Share an insight, caveat, or question.
Stringhini et al. (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: