Population
Mice with doxorubicin-induced cardiomyopathy
Design
Preclinical
Authors
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Does not support TLR4-targeted therapy in patients yet; leaves open translation from murine doxorubicin models.
TLR4 deficiency protects against doxorubicin-induced cardiomyopathy in a mouse model.
Riad et al. (2008) studied this question.
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