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February 1, 2024BMJ Neurology OpenOpen Access

Efficacy and safety of adjunctive oral therapy in Parkinson’s disease with motor complications: a systematic review and network meta-analysis

Vibuthi Sisodia Lars Dubbeld Rob M.A. de Bie Gonçalo S. Duarte João Costa Joke M. Dijk

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Abstract

COMT-Is, DRAs and MAOB-Is effectively reduce motor complications and increase incidence of dyskinesia. In the network meta-analysis, adjunctive use of DRAs appeared most effective.

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Sisodia et al. (2024) studied this question.

synapsesocial.com/papers/69d971fd8988aeabbe6855b8 https://doi.org/10.1136/bmjno-2023-000573

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