Observational study reveals pediatric plasma inorganic pyrophosphate matches adult reference ranges, suggesting the ATP sulfurylase method serves as a reliable diagnostic biomarker tool.
Our results yielded no noteworthy discrepancy to the reported standard range of plasma PPi in adults (2-5 µM). We propose the described ATP sulfurylase method as a diagnostic tool to measure PPi levels in plasma as a biomarker in the pediatric population.
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Bernhard et al. (2021) studied this question.
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