4-5-Methyl-3-phenylisoxazol-4-yl- benzenesulfonamide, Valdecoxib:  A Potent and Selective Inhibitor of COX-2

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1 H -pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)1997 · 1,970 citations
2. 2Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice.1990 · 398 citations
3. 3Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase).1988 · 431 citations
4. 4Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence.1988 · 597 citations