What question did this study set out to answer?

To review the geographic expansion, life cycle, clinical consequences, and clinical management strategies of Angiostrongylus cantonensis infection.

November 7, 2022American Journal of Tropical Medicine and HygieneOpen Access

Neuroangiostrongyliasis: Global Spread of an Emerging Tropical Disease

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Authors

RCRobert H. CowieUniversity of Hawaiʻi at Mānoa VAVernon AnsdellUniversity of Hawaiʻi at Mānoa CDClaire Panosian DunavanUniversity of California, Los Angeles

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Implication

Narrative review reports the global spread and clinical impact of neuroangiostrongyliasis in humans, highlighting the urgent need for medical awareness.

Key Points

To review the geographic expansion, life cycle, clinical consequences, and clinical management strategies of Angiostrongylus cantonensis infection.
Synthesized evidence on the global dissemination of Angiostrongylus cantonensis from Southeast Asia to the Americas, Africa, Australia, and European archipelagos.
Summarized mechanisms of transmission from intermediate mollusk hosts to definitive rat hosts and accidental human hosts, alongside diagnostic and therapeutic practices.
Angiostrongylus cantonensis has successfully spread from southern China into tropical, subtropical, and temperate regions across multiple continents.
Accidental ingestion of infective third-stage larvae induces larval central nervous system migration, precipitating eosinophilic meningitis, severe chronic neurological deficits, and potential death.
Diagnosis remains difficult due to non-specific presentation, while therapy focuses on corticosteroids, anthelminthics, analgesics, and intracranial pressure reduction via therapeutic lumbar punctures.

Cite This Study

Cowie et al. (2022) studied this question.

synapsesocial.com/papers/69d97ead0d540cafc5835d5f https://doi.org/10.4269/ajtmh.22-0360

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Implication

Narrative review reports the global spread and clinical impact of neuroangiostrongyliasis in humans, highlighting the urgent need for medical awareness.

Neuroangiostrongyliasis: Global Spread of an Emerging Tropical Disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Neuroangiostrongyliasis: Global Spread of an Emerging Tropical Disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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