An extra X or Y chromosome: Contrasting the cognitive and motor phenotypes in childhood in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome

Judith L. Ross; Martha P.D. Zeger; Harvey Kushner; Andrew R. Zinn; David P. Roeltgen

doi:10.1002/ddrr.85

January 1, 2009Developmental Disabilities Research ReviewsOpen Access

An extra X or Y chromosome: Contrasting the cognitive and motor phenotypes in childhood in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome

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Key Points

To contrast the cognitive and motor profiles during childhood in boys with 47,XYY syndrome versus 47,XXY Klinefelter syndrome.
Evaluated neurocognitive, motor, and educational profiles across large cohorts of boys diagnosed with 47,XYY syndrome and 47,XXY Klinefelter syndrome.
Identified distinct neurocognitive patterns and motor differences that characterize brain development in each sex chromosome variation.
Showed that boys with both conditions present specific, differentiable learning challenges requiring customized educational support and targeted clinical counseling.

Implication

Cohort study reveals distinct neurocognitive and learning challenges in boys with 47,XYY and Klinefelter syndrome, highlighting the need for tailored educational and clinical interventions.

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Cite This Study

Ross et al. (2009) studied this question.

synapsesocial.com/papers/69d994ed5e5bcb4e3b837142 https://doi.org/10.1002/ddrr.85

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An extra X or Y chromosome: Contrasting the cognitive and motor phenotypes in childhood in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome

Key Points

Implication

Discussion

Cite This Study

An extra X or Y chromosome: Contrasting the cognitive and motor phenotypes in childhood in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome

Key Points

Implication

Discussion

Cite This Study

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