Why the study?
Does ganglion blockade alter dynamic cerebral autoregulation in humans?
Does ganglion blockade alter dynamic cerebral autoregulation in humans?
Autonomic neural control appears to be tonically active and plays a significant role in regulating beat-to-beat cerebral blood flow in humans.
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Autonomic role in cerebral autoregulation supported; hypothesis-generating and should not yet change practice.
These data suggest that dynamic cerebral autoregulation is altered by ganglion blockade. We speculate that autonomic neural control of the cerebral circulation is tonically active and likely plays a significant role in the regulation of beat-to-beat CBF in humans.
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Zhang et al. (2002) studied this question.
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