June 1, 2025New England Journal of Medicine
Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
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Implication
Randomized trial demonstrates improved disease-free survival with exercise in colon cancer, highlighting the benefit of structured activity.
Key Points
- To assess the effect of a 3-year structured exercise program initiated after adjuvant chemotherapy on disease-free and overall survival in patients with colon cancer.
- Interventional clinical trial (CHALLENGE trial, ClinicalTrials.gov number NCT00819208) evaluating a 3-year structured exercise program initiated shortly after the completion of adjuvant chemotherapy for colon cancer.
- Participation in the 3-year structured exercise program led to significantly longer disease-free survival compared to standard follow-up.
- Trial findings were consistent with improved overall survival following the structured exercise intervention.
Cite This Study
Courneya et al. (2025) studied this question.