Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment

Yan Hu; Kristopher M. Kirmess; Matthew R. Meyer; Gil D. Rabinovici; Constantine Gatsonis; Barry A. Siegel; Rachel A. Whitmer; Charles Apgar; Lucy Hanna; Michio Kanekiyo; June Kaplow; Akihiko Koyama; David Verbel; Mary S. Holubasch; S Knapik; Jason Connor; John H. Contois; Erin N. Jackson; Scott E. Harpstrite; Randall J. Bateman; David M. Holtzman; Philip B. Verghese; I. Fogelman; Joel B. Braunstein; Kevin E. Yarasheski; Tim West

doi:10.1001/jamanetworkopen.2022.8392

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Abstract

These findings suggest that this blood biomarker test could allow for distinguishing individuals with brain amyloid-positive PET findings from individuals with amyloid-negative PET findings and serve as an aid for Alzheimer disease diagnosis.

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Hu et al. (2022) studied this question.

synapsesocial.com/papers/69d9a0b38988aeabbe685d46 https://doi.org/10.1001/jamanetworkopen.2022.8392

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Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment

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Abstract

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Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment

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Abstract

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