Why the study?
Myocardial infarction in the absence of obstructive coronary artery disease has a variety of causes, necessitating appropriate diagnosis and evaluation to uncover the underlying cause and prescribe specific therapies.
This American Heart Association scientific statement provides an updated definition and clinical framework for the diagnosis and management of MINOCA.
Standardizes MINOCA diagnosis and management for clinicians; extends prior definitions with actionable algorithms for research.
Myocardial infarction in the absence of obstructive coronary artery disease is found in ≈5% to 6% of all patients with acute infarction who are referred for coronary angiography. There are a variety of causes that can result in this clinical condition. As such, it is important that patients are appropriately diagnosed and an evaluation to uncover the correct cause is performed so that, when possible, specific therapies to treat the underlying cause can be prescribed. This statement provides a formal and updated definition for the broadly labelled term MINOCA (incorporating the definition of acute myocardial infarction from the newly released "Fourth Universal Definition of Myocardial Infarction") and provides a clinically useful framework and algorithms for the diagnostic evaluation and management of patients with myocardial infarction in the absence of obstructive coronary artery disease.
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Tamis‐Holland et al. (2019) studied this question.
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