Key result
MINOCA represents up to 15% of the acute myocardial infarction population and requires multimodality imaging to detect the underlying etiology for personalized, cause-targeted therapy.
Why the study?
There are no standard guidelines on the management of MINOCA patients and detecting the underlying etiology is fundamental to initiate early cause-targeted therapy.
MINOCA is a heterogeneous condition requiring multimodality imaging to identify the underlying etiology and guide personalized, cause-targeted therapy.
May guide etiology detection in MINOCA; leaves open whether cause-targeted therapy improves outcomes.
Myocardial infarction with non-obstructive coronary artery disease (MINOCA) represents a significant proportion (up to 15%) of acute myocardial infarction (AMI) population. MINOCA is diagnosed in patients who fullfilled the fourth universal definition of AMI in the absence of significant obstructive coronary artery disease on coronary angiography. MINOCA is a group of heterogeneous diseases with different pathophysiological mechanisms requiring multimodality imaging. Left ventriculography, cardiac magnetic resonance imaging and intra-coronary imaging (IVUS, OCT) are useful tools playing a pivotal role in the diagnostic work-up. There are no standard guidelines on the management of MINOCA patients and the therapeutic approach is personalized, thereby detecting the underlying aetiology is fundamental to initiate an early appropriate cause-targeted therapy.
No takes yet. Share an insight, caveat, or question.
Matta et al. (2021) conducted a review in Myocardial infarction with non-obstructive coronary artery disease (MINOCA). MINOCA represents up to 15% of the acute myocardial infarction population and requires multimodality imaging to detect the underlying etiology for personalized, cause-targeted therapy.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: