Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 1, 1993Genes & DevelopmentOpen Access

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots.

View Full Paper
Ask AI
Bookmark
Share

Authors

NPNikola P. PavletichMemorial Sloan Kettering Cancer CenterKCKristen A ChambersHoward Hughes Medical InstituteCPCarl O. PaboHarvard University Press

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Pavletich et al. (1993) studied this question.

synapsesocial.com/papers/69d9a74f7f18ff2fefa3c367https://doi.org/10.1101/gad.7.12b.2556
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression1992 · 344 citations
  2. 2Transcriptional Activation by Wild-Type but Not Transforming Mutants of the p53 Anti-Oncogene1990 · 640 citations
  3. 3Wild-type p53 is a cell cycle checkpoint determinant following irradiation.1992 · 1,864 citations