Why the study?
Are pulse wave velocity, augmentation index, and intima-media thickness early indicators of vascular damage in asymptomatic, normotensive hypercholesterolemic children?
Are pulse wave velocity, augmentation index, and intima-media thickness early indicators of vascular damage in asymptomatic, normotensive hypercholesterolemic children?
Pulse wave velocity and augmentation index are early indicators of vascular damage in asymptomatic, normotensive hypercholesterolemic children, highlighting the role of hypercholesterolemia in early arterial mechanical impairment.
May support PWV and AIx as early vascular markers in hypercholesterolemic children; leaves open prospective validation before clinical use.
Our findings show that local and systemic arterial stiffness are increased in asymptomatic, normotensive HCh children, suggesting that HCh plays a key role in arterial mechanical impairment since the paediatric age.
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Riggio et al. (2010) studied this question.
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