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April 18, 2002New England Journal of Medicine5,215 citations

Nonalcoholic Fatty Liver Disease

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PAPaul Angulo

Key Points

  • To explore nonalcoholic fatty liver disease and its implications beyond alcohol abuse.
  • Broad overview of the condition, addressing clinical spectrum and risk factors.
  • Identifies obesity, diabetes, and hyperlipidemia as principal risk factors for disease.
  • Describes a clinical spectrum ranging from asymptomatic steatosis to cirrhosis.

Abstract

Alcohol abuse is the most common cause of fatty liver disease, but it is now apparent that fat deposition in the liver, and its consequences, may occur without alcohol abuse. The principal risk factors are obesity, non-insulin-dependent diabetes mellitus, and hyperlipidemia. The disorder has a wide clinical spectrum, ranging from asymptomatic steatosis to steatohepatitis, fibrosis, and cirrhosis. This article provides a broad overview of this increasingly recognized liver disease.

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Cite This Study

Paul Angulo (2002) studied this question.

synapsesocial.com/papers/69d9affdc7f0c3ae80a3e5b3https://doi.org/10.1056/nejmra011775
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