Key result
Reduced cystathionine γ-lyase and hydrogen sulfide activity drives impaired placental vasculature and maternal hypertension in preeclampsia.
Key points are not available for this paper at this time.
Answers are grounded in this paper and cite their sources.
May implicate CSE/H2S deficiency in preeclampsia; hypothesis-generating and leaves open therapeutic translation.
These results imply that endogenous H2S is required for healthy placental vasculature and that a decrease in CSE/H2S activity may contribute to the pathogenesis of preeclampsia.
No takes yet. Share an insight, caveat, or question.
Wang et al. (2013) studied this question. Decreased cystathionine γ-lyase and endogenous hydrogen sulfide activity contributes to impaired placental vasculature, maternal hypertension, and the pathogenesis of preeclampsia.
Synapse has enriched 10 related papers. Consider them for comparative context: