Serum vancomycin concentration decreases progressively with increasing BMI and the augmentation in CrCl in adult patients. The trough concentration of vancomycin should be continuously monitored for patients with a BMI ≥ 24 kg/m², and the dosage regimen should be adjusted to reach the target trough concentration in these patients to reduce the impact of BMI.
No takes yet. Share an insight, caveat, or question.
Pan et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: