What question did this study set out to answer?

To summarize evolving concepts regarding the enzymatic functions, anatomical distribution, and molecular structure of human angiotensin I-converting enzyme.

October 1, 1990HypertensionOpen Access

Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture.

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Authors

EEErvin G. ErdösGeneral / Preventive / Lipids

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Implication

Review uncovers broader peptide metabolic roles and dual active site structure of angiotensin converting enzyme, highlighting unresolved mechanisms in cardiovascular physiology.

Key Points

To summarize evolving concepts regarding the enzymatic functions, anatomical distribution, and molecular structure of human angiotensin I-converting enzyme.
Narrative synthesis of biochemical assays, tissue distribution studies, and molecular cloning data characterizing human angiotensin I-converting enzyme.
Angiotensin-converting enzyme mediates the metabolism of diverse biologically active peptides across widespread tissues, expanding beyond angiotensin II generation and bradykinin degradation.
Molecular cloning identifies a hydrophobic C-terminal transmembrane anchor and an external domain featuring two homologous regions that contain only one functional active center.

Cite This Study

Ervin G. Erdös (1990) studied this question.

synapsesocial.com/papers/69d9d4b50d540cafc58378bb https://doi.org/10.1161/01.hyp.16.4.363

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Implication

Review uncovers broader peptide metabolic roles and dual active site structure of angiotensin converting enzyme, highlighting unresolved mechanisms in cardiovascular physiology.

Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture.

Discussion

Member takes

Implication

Key Points

Cite This Study

Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture.

Discussion

Member takes

Implication

Key Points

Cite This Study

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