Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis

This is the authors' abstract. We don't add key points for this paper.

Using two different and complementary approaches (flow cytometry and immunohistochemistry) on two independent cohorts of ovarian cancer patients, we found that accumulation of plasmacytoid dendritic cells (pDC) in tumors is associated with early relapse. This deleterious effect of tumor-associated pDC was evident when they are present in cancer epithelium but not in lymphoid aggregates.