Are single pill low-dose combinations with 3 or 4 blood pressure-lowering medications effective and safe as an initial treatment option for hypertension?
Single pill low-dose combinations of 3 or 4 antihypertensive medications are an effective and safe initial treatment strategy, with efficacy dependent on baseline blood pressure.
Single pill LDCs are effective and safe as an initial treatment option for hypertension. The degree of BP reduction depends strongly on pretreatment BP level.
Wang et al. (Wed,) studied this question.