Demonstrates the effects of tranexamic acid on mortality and outcomes in trauma patients, suggesting a potential benefit over risks.
For trauma patients with life-threatening hemorrhage, especially those in hemorrhagic shock, it is recommended that TXA be given as early as possible (before arrival in the hospital) in a single dose of 1-2 g (15-30 mg/kg body weight [BW]). When this is done, the benefit appears to be greater than the thromboembolic risk.
No takes yet. Share an insight, caveat, or question.
Lier et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: