Does the dose of intrathecal bupivacaine affect successful intraoperative anesthesia in morbidly obese and nonobese patients undergoing cesarean delivery?
Intrathecal bupivacaine doses below 10 mg may be insufficient for cesarean delivery anesthesia, with no difference in response between obese and nonobese patients.
Obese and nonobese patients undergoing cesarean delivery do not appear to respond differently to modest doses of intrathecal bupivacaine. This dose-response study suggests that doses of intrathecal bupivacaine less than 10 mg may not adequately ensure successful intraoperative anesthesia. Even when the initial block obtained with a low dose is satisfactory, it will not guarantee adequate anesthesia throughout surgery.
Carvalho et al. (Thu,) studied this question.