Answers are grounded in this paper and cite their sources.
Systematic review shows intraindividual pain variability relates to clinical measures in chronic pain, suggesting implications for treatment.
Our findings provide evidence of intraindividual variability in pain intensity in patients with pain conditions that includes nociplastic pain mechanisms, regardless of precise diagnosis. Preliminary evidence suggests that degree of intraindividual pain variability may be associated with measures of clinical relevance, including mental health, fatigue, physical activity level, and drug and placebo response.
No takes yet. Share an insight, caveat, or question.
Klinke et al. (2026) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: