Renal medullary carcinoma: a systematic review of clinical and radiological findings

William B. N. Weston; Cherry Sit; Derfel ap Dafydd; Christian Kelly-Morland; Aslam Sohaib; Shraddha Adamane; Thubeena Manickavasagar; L. Pickering; David Nicol; Samuel J. Withey

doi:10.1007/s11255-026-05113-4

April 9, 2026International Urology and NephrologyOpen Access

Renal medullary carcinoma: a systematic review of clinical and radiological findings

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to summarize clinical and radiological characteristics of renal medullary carcinoma (RMC).
Conducted a systematic review of clinical and radiological findings related to RMC.
Included cases regardless of sickle cell status.
Analyzed survival rates in relation to metastatic spread.
RMC typically presents at a relatively young age.
Most cases are advanced at presentation.
Poor overall survival is observed in patients with nodal or distant metastases.

Implication

Systematic review reveals poor survival with advanced renal medullary carcinoma, regardless of sickle cell status.

Abstract

Regardless of sickle cell status, RMC was shown to present at a relatively young age. It was classically seen as an infiltrative, poorly defined, endophytic tumour, centred on the renal medulla. RMC was found to be more commonly advanced at presentation and the overall survival in patients with nodal or distant metastases was poor.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Weston et al. (2026) studied this question.

synapsesocial.com/papers/69d9e5ec78050d08c1b7634c https://doi.org/10.1007/s11255-026-05113-4

View Full Paper

Ask AI

Bookmark

Share

Renal medullary carcinoma: a systematic review of clinical and radiological findings

Key Points

Implication

Abstract

Discussion

Cite This Study

Renal medullary carcinoma: a systematic review of clinical and radiological findings

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading