Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

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Key Points

This research examines how the fluid replacement method influences solute removal performance and biocompatibility during hemodiafiltration.
Utilized the asymmetric cellulose triacetate membrane for hemodiafiltration.
Conducted comparisons of pre- and post-hemodiafiltration performance.
Evaluated biocompatibility and solute removal efficiency.
Post-hemodiafiltration (Post-HDF) exhibited superior solute removal compared to pre-hemodiafiltration.
Both pre- and post-HDF showed comparable levels of biocompatibility.

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Experiment demonstrates improved solute removal in hemodiafiltration, suggesting better performance with specific membrane technologies.

Using the ATA membrane, Pre- and Post-HDF showed comparable biocompatibility, while Post-HDF provided superior solute removal performance.

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Sakurai et al. (2026) studied this question.

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