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Case report demonstrates disease-free survival in a young woman following fertility-sparing surgery for early-stage cervical cancer, highlighting potential benefits.
Background Fertility‐sparing surgery is an increasingly accepted option in carefully selected patients with early‐stage cervical cancer. Radical vaginal trachelectomy combined with sentinel lymph node (SLN) mapping offers oncologic safety while preserving reproductive potential. Case A 29‐year‐old nulliparous woman with FIGO stage IB1 poorly differentiated HPV‐associated mucinous cervical adenocarcinoma with signet‐ring cell features underwent radical vaginal trachelectomy and bilateral laparoscopic SLN mapping using indocyanine green (ICG). No nodal metastases were identified. Surgical margins were negative, and an abdominal cervical cerclage was placed. At 24 months of follow‐up, the patient remains disease‐free and is receiving counseling regarding assisted reproductive technologies. Conclusion Fertility‐preserving surgery may be safely performed in selected early‐stage cervical cancer patients when combined with appropriate surgical staging and close follow‐up. This case adds to the limited literature regarding the conservative management of high‐grade mucinous adenocarcinomas with signet‐ring cell morphology.
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Ortiz et al. (2026) studied this question.
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