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April 11, 2026Journal of materials research/Pratt's guide to venture capital sourcesOpen Access

4D degradation analysis of gelatin-modified calcium/strontium phosphate bone substitutes with µCT-flow chamber

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Authors

CGCeline GuderPBPaul BertramFAFranziska Alt

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Overview

Dynamic degradation analysis reveals mass loss and ion release in gelatin-modified bone substitutes, indicating improved material evaluation.

Key Points

  • To analyze the degradation behavior of gelatin-modified calcium/strontium phosphate composites under controlled flow conditions.
  • Utilized a custom degradation chamber with varying flow rates (0.022 and 0.266 mL/min) for seven days
  • Conducted µCT imaging to assess degradation of gelatin and Ca/Sr phosphate separately
  • Measured mass loss and ion concentration to evaluate degradation dynamics
  • Identified time-resolved degradation of organic and inorganic components using µCT
  • Higher flow rates resulted in 5% greater mass loss due to shear stresses
  • Enhanced ion release was observed at increased flow rates, indicating accelerated degradation

Cite This Study

Guder et al. (2026) studied this question.

synapsesocial.com/papers/69d9e66378050d08c1b76bcbhttps://doi.org/10.1557/s43578-026-01828-3
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