Why the study?
Does the measurement of very high and very low levels of hsCRP provide useful prognostic information for cardiovascular risk across the full range of Framingham Risk Scores?
Does the measurement of very high and very low levels of hsCRP provide useful prognostic information for cardiovascular risk across the full range of Framingham Risk Scores?
hsCRP levels, including very low and very high extremes, are clinically useful for cardiovascular risk prediction across all Framingham Risk Scores.
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hsCRP extremes may refine CV risk stratification across Framingham scores; leaves open prospective outcome trials before routine adoption.
Both very low (<0.5 mg/L) and very high (>10 mg/L) levels of hsCRP provide important prognostic information on cardiovascular risk. hsCRP is clinically useful for risk prediction across a full range of values and across a full range of FRS.
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Ridker et al. (2004) studied this question.
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