Does the measurement of very high and very low levels of hsCRP provide useful prognostic information for cardiovascular risk across the full range of Framingham Risk Scores?
hsCRP levels, including very low and very high extremes, are clinically useful for cardiovascular risk prediction across all Framingham Risk Scores.
Both very low (10 mg/L) levels of hsCRP provide important prognostic information on cardiovascular risk. hsCRP is clinically useful for risk prediction across a full range of values and across a full range of FRS.
Ridker et al. (2004) studied this question.