CoCAPHot Line 11Cardiac Surgery
Graft Patency After Coronary Artery Bypass Grafting With Dual Antiplatelet Therapy or Aspirin
Graft patency in patients with acute coronary syndrome treated with dual antiplatelet therapy or aspirin alone after coronary artery bypass grafting
Presenting authorJonas HolmCross-Cutting Cardiology · Linköping University Hospital, SwedenJonas Holm is an Adjunct Associate Professor and Docent in Cardiothoracic Surgery at Linköping University. He works as a senior consultant (överläkare) in the Department of Thoracic and Vascular Surgery at Linköping University Hospital (Region Östergötland Heart Center). His research focuses on diagnostics and treatment in cardiac surgery, including biomarkers for heart failure, metabolic interventions, and computed tomography evaluation of vascular grafts after coronary bypass surgery.
Overview
Awaiting this RCT's graft patency results in ACS post-CABG; leaves open optimal antiplatelet regimen until ESC 2026.
Key result
Dual antiplatelet therapy versus aspirin alone for graft patency in patients with acute coronary syndrome after coronary artery bypass grafting has pending results.
Discussion
Expert reaction lands here the moment CoCAP reports.
Key Points
- Graft patency is evaluated in patients presenting with acute coronary syndrome to compare dual antiplatelet therapy directly against aspirin alone after coronary artery bypass grafting.
- Evaluation focuses on vessel openness following bypass surgery across antiplatelet regimens, with official clinical trial findings pending presentation at the ESC Congress 2026.
- Clinical trial assessment addresses post-surgical management in coronary artery disease, highlighting optimal antiplatelet regimens to preserve surgical graft patency over time.
Structured PICO
Does dual antiplatelet therapy improve graft patency in patients with acute coronary syndrome after coronary artery bypass grafting compared to aspirin alone?
P
Population
Patients with acute coronary syndrome after coronary artery bypass grafting
I
Intervention
Dual antiplatelet therapy
C
Comparator
Aspirin alone
O
Outcome
Graft patencysurrogate
Main Result
Absolute Event Rate: 0% vs 0%