April 19, 2020SHILAP Revista de lepidopterologíaOpen Access

Frailty is an independent risk factor for recurrence and mortality following curative resection of stage I–III colorectal cancer

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Why the study?

Does preoperative frailty affect recurrence-free and overall survival in patients undergoing curative resection of stage I-III colorectal cancer?

Population

Patients undergoing resection of nonmetastatic colorectal cancer

Comparison

Preoperative frailty vs non-frailty

Authors

KMKosuke MimaKumamoto Medical Center NMNobutomo MiyanariKumamoto Medical Center AMAtsushi MoritoJapanese Foundation For Cancer Research

Discussion

Member takes

Implication

May aid preoperative risk stratification; leaves open whether frailty interventions improve survival after colorectal cancer resection.

Structured PICO

Does preoperative frailty affect recurrence-free and overall survival in patients undergoing curative resection of stage I-III colorectal cancer?

Population

Patients undergoing curative resection of stage I-III (nonmetastatic) colorectal cancer

Intervention

Preoperative frailty (exposure)

Outcome

Recurrence-free survival (RFS) and overall survival (OS)hard clinical

Preoperative frailty serves as an independent prognostic factor for worse recurrence-free and overall survival in nonmetastatic colorectal cancer patients.

Cite This Study

Mima et al. (2020) studied this question.

synapsesocial.com/papers/69da10caa1d151c65f6858e9 https://doi.org/10.1002/ags3.12337

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Frailty is an independent risk factor for recurrence and mortality following curative resection of stage I–III colorectal cancer

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Frailty is an independent risk factor for recurrence and mortality following curative resection of stage I–III colorectal cancer

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider