Population
Normal human subjects and patients with dyslipoproteinemia
Design
Cross-sectional
Authors
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GSL elevations in HoFH support lipoprotein association; hypothesis-generating and requires prospective validation before any clinical or mechanistic inference.
Glycosphingolipids are intimately associated with serum lipoproteins in both normal and dyslipoproteinemic states, with significant elevations seen in homozygous familial hypercholesterolemia.
Dawson et al. (1976) studied this question.
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