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October 5, 2023Diabetes Obesity and MetabolismOpen Access

Abolishing β‐arrestin recruitment is necessary for the full metabolic benefits of G protein‐biased glucagon‐like peptide‐1 receptor agonists

Charlotte E. Hinds Ellie Peace Shiqian Chen Iona Davies Liliane El Eid Alejandra Tomás Tricia Tan James Minnion Ben Jones Stephen R. Bloom

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Abstract

Completely abolishing β-arrestin recruitment improves the anti-hyperglycaemic effects of GLP-1R agonists in mice.

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Hinds et al. (2023) studied this question.

synapsesocial.com/papers/69da225e1e2c7d7b4fa3bf92 https://doi.org/10.1111/dom.15288

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