Why the study?
Do exercise stress echocardiography parameters and aortic valve replacement predict long-term mortality in asymptomatic patients with severe aortic stenosis and preserved LVEF?
Do exercise stress echocardiography parameters and aortic valve replacement predict long-term mortality in asymptomatic patients with severe aortic stenosis and preserved LVEF?
In asymptomatic patients with severe aortic stenosis and preserved LVEF, poor exercise capacity and slower heart rate recovery on stress echocardiography predict mortality, while aortic valve replacement improves survival.
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May refine mortality risk stratification in asymptomatic severe AS; leaves open whether exercise parameters should guide AV replacement timing.
In asymptomatic patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing exercise stress echocardiography, a lower % of age-sex-predicted METs and slower heart rate recovery were associated with longer-term mortality, whereas AV replacement was associated with improved survival.
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Masri et al. (2016) studied this question.
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