Why the study?
Is fibrinogen level associated with major bleeding risk in patients receiving tPA for acute lower extremity intravascular thrombosis?
Population
Patients with acute lower extremity intravascular thrombosis
Design
Other
Authors
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Suggests fibrinogen monitoring may identify bleeding risk during tPA; hypothesis-generating and requires prospective validation before practice change.
Is fibrinogen level associated with major bleeding risk in patients receiving tPA for acute lower extremity intravascular thrombosis?
Serial fibrinogen measurement may be a viable method to monitor bleeding risk during lower extremity tPA infusions.
Skeik et al. (2013) studied this question.
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