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Aedes aegyptiuses RNA interference in defense against Sindbis virus infection | Synapse

March 17, 2008Open Access

Aedes aegyptiuses RNA interference in defense against Sindbis virus infection

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Resumen

We show that silencing RNAi components in Ae. aegypti results in transient increases in SINV replication. Furthermore, Ae. aegypti RNAi is active during SINV infection as indicated by production of virus-specific siRNAs. Lastly, the RNAi response varies in a virus-dependent manner. These data define important features of RNAi anti-viral defense in Ae. aegypti.

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Cite This Study

Campbell et al. (Mon,) studied this question.

synapsesocial.com/papers/69da2861a6045d71bfa3c43b https://doi.org/https://doi.org/10.1186/1471-2180-8-47