Why the study?
Does inhibition of ACE accelerate bone healing and remodelling in a fracture model?
Does inhibition of ACE accelerate bone healing and remodelling in a fracture model?
Inhibition of ACE accelerates bone healing and remodeling, suggesting a role for a local renin-angiotensin system in bone.
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ACE inhibition may accelerate bone healing in animal models; leaves open translation to human fracture care.
Our study provides evidence for a local RAS in bone that influenced the process of fracture healing. We show for the first time that inhibition of ACE is capable of accelerating bone healing and remodelling.
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García et al. (2010) studied this question.
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