Why the study?
Does optimal medical treatment lead to persistent recovery of normal left ventricular function and dimension in patients with idiopathic dilated cardiomyopathy?
Does optimal medical treatment lead to persistent recovery of normal left ventricular function and dimension in patients with idiopathic dilated cardiomyopathy?
A remarkable proportion of patients with idiopathic dilated cardiomyopathy on optimal medical therapy show persistent recovery of LV function, though very long-term decline can occur, necessitating ongoing follow-up.
Necessitates lifelong surveillance after apparent LV recovery in dilated cardiomyopathy; leaves open predictors of sustained remission.
Persistent long-term apparent healing was evident in a remarkable proportion of dilated cardiomyopathy patients receiving optimal medical treatment and was associated with stable normalization of main clinical and laboratory features. This condition can be characterized by a decline of left ventricular function over the very long term, highlighting the relevance of serial nd individualized follow-up in all patients with dilated cardiomyopathy, especially considering the absence of predictors for longterm apparent healing.
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Merlo et al. (2015) studied this question.
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