Why the study?
Does Coronary endothelial function (CEF) testing improve prediction of cardiovascular events compared to standard clinical risk scoring in patients presenting with chest pain or suspected ischemia?
Does Coronary endothelial function (CEF) testing improve prediction of cardiovascular events compared to standard clinical risk scoring in patients presenting with chest pain or suspected ischemia?
Coronary endothelial function testing provides superior risk discrimination for cardiovascular events compared to the Framingham Risk Score alone in patients with chest pain or suspected ischemia.
Answers are grounded in this paper and cite their sources.
CEF testing may refine risk stratification beyond FRS in chest pain; hypothesis-generating and requires prospective validation before practice change.
CEF testing is safe and adds value to the FRS, with superior discrimination and risk stratification compared with FRS alone in patients presenting with chest pain or suspected ischemia.
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Reriani et al. (2016) studied this question.
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