Why the study?
Does inherited thrombophilia affect the risk, localization, and timing of pregnancy-related VTE?
Does inherited thrombophilia affect the risk, localization, and timing of pregnancy-related VTE?
Inherited thrombophilia not only increases the risk of pregnancy-related VTE but also influences the anatomical localization of the thrombosis.
Answers are grounded in this paper and cite their sources.
May refine anatomic risk stratification for pregnancy-related VTE; leaves open whether testing improves outcomes.
Inherited thrombophilia was found to be considerably more frequently present in women with pregnancy- and puerperium-related VTE compared to healthy controls. Women with thrombophilia are at higher risk of developing thromboses localized in the iliacofemoral region, and women without thrombophilia are at higher risk of developing pulmonary embolism. Deficiency in natural coagulation inhibitors is associated with antepartum VTE occurrence.
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Mitić et al. (2011) studied this question.
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