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November 1, 1993CirculationOpen Access

Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.

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Why the study?

Is cigarette smoking associated with impaired endothelium-dependent arterial dilation in healthy young adults?

Population

Asymptomatic healthy young adults

Design

Cross-sectional

Authors

David S. Celermajer
David S. CelermajerAdult Congenital Heart Disease
KSKeld E. SørensenPediatric / Congenital CardiologyDGDimitri GeorgakopoulosUniversity High School

Discussion

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Implication

May support early smoking avoidance counseling; leaves open prospective confirmation of dose-dependent reversibility.

Structured PICO

Is cigarette smoking associated with impaired endothelium-dependent arterial dilation in healthy young adults?

P
Population
Asymptomatic healthy young adults
I
Intervention
Cigarette smoking
O
Outcome
Endothelium-dependent arterial dilationsurrogate

Cigarette smoking is associated with dose-dependent, reversible endothelial dysfunction in asymptomatic young adults.

Cite This Study

Celermajer et al. (1993) studied this question.

synapsesocial.com/papers/69da2ee20d540cafc5838d25https://doi.org/10.1161/01.cir.88.5.2149
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