Population
Neurons/in vitro models expressing KCNQ2 and KCNQ3 potassium channels
Design
Preclinical
Authors
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Confirms KCNQ2/3 contribution to M-current in animal neurons; leaves open human translation and therapeutic targeting.
KCNQ2 and KCNQ3 potassium channel subunits are identified as molecular correlates of the M-channel, which regulates neuronal excitability.
H. Wang (1998) studied this question.
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