What question did this study set out to answer?

To examine the statistical behavior of standardized gene frequency variance in random mating populations and derive new formulae for estimating effective population size.

July 1, 1981GeneticsOpen Access

Genetic Drift and Estimation of Effective Population Size

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Authors

MNMasatoshi NeiRutgers, The State University of New Jersey FTFumio TajimaThe University of Tokyo

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Implication

Statistical analysis demonstrates estimation of effective population size from gene frequency variance in random mating populations, indicating effective size is often far below census counts.

Key Points

To examine the statistical behavior of standardized gene frequency variance in random mating populations and derive new formulae for estimating effective population size.
Analyzed the statistical properties of the standardized variance of temporal gene frequency changes, corresponding to Wright's inbreeding coefficient.
Evaluated estimation accuracy relative to the ratio of sample size to effective size, generation intervals (t), and the number of examined loci or alleles.
Applied the estimation formulae to empirical allele frequency data collected from an isolated population of Dacus oleae.
Demonstrated that the standardized variance approximately follows a chi-square distribution unless generation intervals (t) are extremely large, providing a method to calculate confidence intervals.
Calculated that the effective population size of the isolated Dacus oleae population was approximately one-tenth of its minimum observed census size.

Cite This Study

Nei et al. (1981) studied this question.

synapsesocial.com/papers/69da55d5a6045d71bfa3c910 https://doi.org/10.1093/genetics/98.3.625

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Implication

Statistical analysis demonstrates estimation of effective population size from gene frequency variance in random mating populations, indicating effective size is often far below census counts.

Genetic Drift and Estimation of Effective Population Size

Discussion

Member takes

Implication

Key Points

Cite This Study

Genetic Drift and Estimation of Effective Population Size

Discussion

Member takes

Implication

Key Points

Cite This Study

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