Global, regional, and national burden of chronic kidney disease in adults, 1990–2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023
Key result
CKD affects ~14% of adults globally and remains a major driver of worldwide mortality.
- Relative rise 3.5%
- 95% CI 13.4-15.2
Population
Adults aged 20 years and older from 204 countries and territories over the period 1990 to 2023.
Design
Meta-analysis
Follow-up
1990 to 2023
Authors
Discussion
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Member takes
Implication
Rising CKD burden warrants expanded screening and risk factor control in practice; extends global estimates and highlights CVD links for targeted research.
Study Design
Type
Systematic Review
Multicenter
Yes
Structured PICO
P
Population
Adults aged 20 years and older from 204 countries and territories over the period 1990 to 2023.
O
Outcome
Estimates of CKD burden, including deaths, incidence, prevalence, and disability-adjusted life-years (DALYs)
Main Result
Effect estimate: Relative rise 3.5% (95% CI 13.4-15.2)
CKD prevalence is rising globally, affecting an estimated 788 million adults in 2023 and contributing significantly to cardiovascular mortality.
Limitations
- Not reported in the provided text
Cite This Study
Mark et al. (2025) conducted a systematic review in Chronic kidney disease. Chronic kidney disease affected an estimated 788 million adults globally in 2023, with an age-standardised prevalence of 14.2% and accounting for 1.48 million deaths.