January 1, 1986Biometrika
A case-cohort design for epidemiologic cohort studies and disease prevention trials
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Overview
Randomized trial proposes a case-cohort design for estimating failure rates in epidemiologic studies, suggesting new methodologies.
Key Points
- To introduce a case-cohort design that links failure rates to covariate histories in epidemiological research.
- Proposed a design utilizing covariate data for failures and a randomly selected subcohort.
- Presented estimation procedures for odds ratios and relative risks.
- Conducted a small simulation study comparing the new case-cohort procedures to traditional methods.
- Demonstrated that case-cohort estimations are feasible in estimating relative risks.
- Comparisons showed that the case-cohort method is simpler than full-cohort and synthetic case-control methods.
Cite This Study
Ross L. Prentice (1986) studied this question.