Why the study?
Does adding opioids to intrathecal local anesthetics improve postoperative analgesia in adults undergoing minor surgery?
Does adding opioids to intrathecal local anesthetics improve postoperative analgesia in adults undergoing minor surgery?
Adding morphine or fentanyl to intrathecal local anesthetics prolongs postoperative analgesia but increases the risk of adverse effects like pruritus, nausea, and urinary retention, with no evidence of dose-responsiveness for benefits or harms.
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Supports intrathecal opioids for extended analgesia in minor surgery; confirms RCT efficacy while highlighting pruritus, nausea, and retention risks.
Pöpping et al. (2012) studied this question.
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