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November 30, 1990Science

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

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Authors

DMDavid MalkinUniversity of TorontoFLFrederick P. LiDana-Farber Cancer InstituteLSLouise C. StrongThe University of Texas MD Anderson Cancer Center

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Cite This Study

Malkin et al. (1990) studied this question.

synapsesocial.com/papers/69da6e8f0f778bd2e4684d10https://doi.org/10.1126/science.1978757
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.1988 · 1,134 citations
  2. 2Soft-Tissue Sarcomas, Breast Cancer, and Other Neoplasms1969 · 1,516 citations
  3. 3Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas1989 · 2,095 citations
  4. 4Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial Deletion1978 · 728 citations
  5. 5p53: A Frequent Target for Genetic Abnormalities in Lung Cancer1989 · 1,231 citations